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You're also free to select a transplant center on your own or choose a center from your insurance company's list of preferred providers. If your doctor recommends a liver transplant, you may be referred to a transplant center. How you prepare Choosing a transplant center Your doctor may give you medications to help you fight infections.
These anti-rejection medications can cause a variety of side effects, including:īecause anti-rejection drugs work by suppressing the immune system, they also increase risk of infection. Anti-rejection medication side effectsĪfter a liver transplant, you'll take medications for the rest of your life to help prevent your body from rejecting the donated liver. Long-term complications may also include the liver disease returning in the transplanted liver. Bile duct complications, including bile duct leaks or shrinking of the bile ducts.Risks associated with the procedure include: There are risks associated with the procedure itself and with the drugs necessary to prevent rejection of the donor liver after the transplant. Liver transplant surgery carries a risk of significant complications. Liver transplant may also treat certain cancers that originate in the liver. Biliary atresia is the most common reason for liver transplant among children. They include primary biliary cirrhosis, primary sclerosing cholangitis and biliary atresia. Diseases that affect the tubes that carry bile away from the liver (bile ducts).They include hemochromatosis, which causes excessive iron buildup in the liver, and Wilson's disease, which causes excessive copper buildup in the liver. Nonalcoholic fatty liver disease, a condition in which fat builds up in the liver, causing inflammation or liver cell damage.Alcoholic liver disease, which causes damage to the liver due to excessive alcohol consumption.Major causes of cirrhosis leading to liver failure and liver transplant include: Cirrhosis is the most frequent reason for a liver transplant. When cirrhosis occurs, scar tissue replaces typical liver tissue and the liver doesn't function properly. The most common cause of chronic liver failure is scarring of the liver (cirrhosis). Chronic liver failure occurs slowly over months and years.Ĭhronic liver failure may be caused by a variety of conditions. Acute liver failure is an uncommon condition that is usually the result of complications from certain medications.Īlthough a liver transplant may treat acute liver failure, it is more often used to treat chronic liver failure. Liver failure that occurs quickly, in a matter of weeks, is called acute liver failure. Liver failure may happen quickly or over a long period of time. Liver transplant is a treatment option for some people with liver cancer and for people with liver failure whose condition can't be controlled with other treatments. In cirrhosis (right), scar tissue replaces healthy liver tissue. At the same time, about 12,800 people were registered on the waiting list for a liver transplant.Ī typical liver (left) shows no signs of scarring. Of those, about 390 involved livers from living donors. In 2018, about 8,200 liver transplants were performed in the U.S. Living-donor liver transplant is possible because the human liver regenerates and returns to its normal size shortly after surgical removal of part of the organ. Receiving a portion of a liver from a living donor is an alternative to waiting for a deceased-donor liver to become available. The number of people waiting for a liver transplant greatly exceeds the number of available deceased-donor livers. Liver transplant may also be a treatment option in rare cases of sudden failure of a previously healthy liver. Liver transplant is usually reserved as a treatment option for people who have significant complications due to end-stage chronic liver disease. Preventing infection and regulating immune responses.Removing bacteria and toxins from the blood.Making proteins that help the blood clot.Producing bile, which helps the body absorb fats, cholesterol and fat-soluble vitamins.Processing nutrients, medications and hormones.
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